When you hear DAPT, Dual Antiplatelet Therapy, a combination of two drugs that prevent blood clots by stopping platelets from sticking together. Also known as dual antiplatelet therapy, it’s a standard after heart attacks, stents, or certain types of stroke — and skipping it can be dangerous. DAPT isn’t just one drug. It’s two: usually aspirin, a common over-the-counter pain reliever that also blocks platelet activity and clopidogrel, a prescription antiplatelet that works differently to stop clots from forming. Together, they keep blood flowing through narrowed or repaired arteries. But they’re not harmless — bleeding risks go up, and timing matters.
Doctors don’t hand out DAPT lightly. It’s typically prescribed after a stent is placed in a heart artery, or after a heart attack. The goal? Prevent another clot from forming inside the stent or elsewhere. Studies show that stopping DAPT too early — even just a few weeks after starting — can double the chance of another heart attack. But taking it too long? That raises your risk of serious bleeding, like in the stomach or brain. That’s why most people take it for 6 to 12 months, then switch to just aspirin. Some high-risk patients stay on it longer. It’s not one-size-fits-all. Your age, other health issues, and even your genetics can change what’s right for you.
You’ll find posts here that dig into the real-world details: how DAPT compares with newer drugs like ticagrelor or prasugrel, why some people don’t respond to clopidogrel, and what to do if you need surgery while on DAPT. There’s also info on managing side effects — like bruising, nosebleeds, or stomach upset — without stopping treatment. You’ll see how DAPT fits into bigger pictures: heart disease, stroke prevention, and even how other meds like acid reducers can interfere with its effectiveness. This isn’t theory. These are the exact topics covered in posts about anticoagulant reversal, drug interactions, and medication safety. If you’re on DAPT, or someone you care about is, this collection gives you the facts you need to ask the right questions — and stay safe.
Dual antiplatelet therapy reduces heart attacks after stent surgery but increases bleeding risk. Learn how to manage bleeding side effects with the latest guidelines, drug choices, and proven strategies like de-escalation and shortened treatment.
More